Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 11/20 | 0.58 |
| ▸ | SRD5A1 | P18405 | 5/20 | 0.58 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8803459 | 0.88 | SRD5A2 (0.64) | SRD5A2SRD5A1ESR1ARESR2 | |
| SCHEMBL8801969 | 0.88 | SRD5A2 (0.76) | SRD5A2SRD5A1 | |
| SCHEMBL8394055 | 0.87 | SRD5A2 (0.75) | SRD5A2SRD5A1 | |
| SCHEMBL9015172 | 0.83 | SRD5A2 (0.75) | SRD5A2SRD5A1 | |
| SCHEMBL8802576 | 0.81 | SRD5A2 (0.59) | SRD5A2SRD5A1 | |
| SCHEMBL8914483 | 0.80 | SRD5A2 (0.61) | SRD5A2SRD5A1ESR1ARESR2 | |
| SCHEMBL8802546 | 0.79 | SRD5A2 (0.53) | SRD5A2SRD5A1ESR1ARESR2 | |
| SCHEMBL8913873 | 0.79 | SRD5A2 (0.59) | SRD5A2SRD5A1ESR1ARESR2 | |
| SCHEMBL8803098 | 0.79 | SRD5A2 (0.54) | SRD5A2SRD5A1 | |
| SCHEMBL8915278 | 0.78 | SRD5A2 (0.62) | SRD5A2SRD5A1ESR1ARESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0540717-B1 | UNSATURATED 17$g(b)-SUBSTITUTED 3-CARBOXY STEROIDS | PHARMACIA & UPJOHN SPA (IT) | 1997-07-23 | — | — | EP | claimed |