Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8801730 | 0.90 | EDNRB (0.81) | EDNRBEDNRA | |
| SCHEMBL8662783 | 0.89 | EDNRB (0.67) | EDNRBEDNRA | |
| SCHEMBL8657549 | 0.89 | EDNRB (0.80) | EDNRBEDNRA | |
| SCHEMBL8801001 | 0.89 | EDNRB (0.71) | EDNRBEDNRA | |
| SCHEMBL8802228 | 0.89 | EDNRB (0.68) | EDNRBEDNRA | |
| SCHEMBL8800616 | 0.88 | EDNRB (0.62) | EDNRBEDNRA | |
| SCHEMBL7481169 | 0.88 | EDNRB (0.68) | EDNRBEDNRA | |
| SCHEMBL8660648 | 0.88 | EDNRB (0.67) | EDNRBEDNRA | |
| SCHEMBL8660604 | 0.86 | EDNRB (0.57) | EDNRBEDNRA | |
| SCHEMBL8800629 | 0.86 | EDNRB (0.56) | EDNRBEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0658548-B1 | Benzenesulfonamide derivative and process for preparing thereof | TANABE SEIYAKU CO (JP) | 1997-11-19 | — | — | EP | disclosed |
| US-5589478-A | ENDOTHELIN ANTAGONISTS | TANABE SEIYAKU CO., LTD. (JP) | 1996-12-31 | — | — | US | disclosed |
| EP-0658548-A1 | Benzenesulfonamide derivative and process for preparing thereof | TANABE SEIYAKU CO., LTD. (JP) | 1995-06-21 | — | — | EP | disclosed |