Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | ANPEP | P15144 | 1/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7098611 | 0.89 | KMT2A (0.55) | KMT2ACYP2D6CYP2C9CYP2C19POLB | |
| SCHEMBL7102243 | 0.89 | KMT2A (0.55) | KMT2ACYP2D6CYP2C9CYP2C19POLB | |
| SCHEMBL7866857 | 0.86 | KMT2A (0.81) | KMT2ACYP2D6CYP2C9CYP2C19POLB | |
| Hydrochloric Acid SCHEMBL27729415 | 0.84 | KMT2A (0.78) | KMT2ACYP2D6CYP2C9CYP2C19POLB | |
| SCHEMBL31126659 | 0.84 | KMT2A (0.63) | KMT2ACYP2D6CYP2C9CYP2C19POLB | |
| SCHEMBL23775683 | 0.83 | POLB (0.66) | KMT2ACYP2D6CYP2C9CYP2C19POLB | |
| SCHEMBL7545242 | 0.83 | KMT2A (0.61) | KMT2ACYP2D6CYP2C9CYP2C19POLB | |
| SCHEMBL7437248 | 0.83 | KMT2A (0.61) | KMT2ACYP2D6CYP2C9CYP2C19POLB | |
| SCHEMBL6190815 | 0.83 | KMT2A (0.61) | KMT2ACYP2D6CYP2C9CYP2C19POLB | |
| SCHEMBL15311172 | 0.83 | KMT2A (0.61) | KMT2ACYP2D6CYP2C9CYP2C19POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805810-A1 | NOVEL 9H-PYRIDO 3,4-B]INDOL DERIVATIVES | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-11-12 | — | — | EP | disclosed |
| WO-1996022989-A1 | NOVEL 9H-PYRIDO[3,4-B]INDOL DERIVATIVES | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-08-01 | — | — | WO | disclosed |