Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | AGER | Q15109 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL118736 | 0.84 | HTT (0.56) | KDM4ETDP1ALDH1A1CYP3A4MAPT | |
| SCHEMBL30867034 | 0.84 | HTT (0.56) | KDM4ETDP1ALDH1A1CYP3A4MAPT | |
| SCHEMBL29286 | 0.82 | KDM4E (0.44) | MAPK1KDM4ETDP1ALDH1A1CYP3A4 | |
| SCHEMBL7841693 | 0.79 | CA12 (0.52) | ALDH1A1KMT2AMEN1 | |
| Phenol SCHEMBL29212150 | 0.79 | HTT (0.50) | KDM4ETDP1ALDH1A1CYP3A4MAPT | |
| SCHEMBL28080607 | 0.75 | HTT (0.62) | MAPK1KDM4ETDP1ALDH1A1MAPT | |
| SCHEMBL9275209 | 0.75 | ELANE (0.44) | KDM4ETDP1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8427946 | 0.75 | MAPT (0.54) | KDM4ETDP1ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL1401811 | 0.74 | CTNNB1 (0.58) | MAPK1KDM4ETDP1ALDH1A1MAPT | |
| SCHEMBL547649 | 0.74 | KDM4E (0.53) | KDM4ETDP1ALDH1A1CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0472113-B1 | Pyrimidine derivatives and herbicidal compositions containing the same | KUMIAI CHEMICAL INDUSTRY CO (JP) | 1997-04-16 | — | — | EP | disclosed |
| US-5154750-A | PYRIMIDIEN DERIVATIVES AND HERBICIDAL COMPOSITIONS CONTAINING THE SAME | KUMIAI CHEMICAL INDUSTRY CO. LTD. (JP) | 1992-10-13 | — | — | US | disclosed |
| US-5114463-A | Bispyrimidinyloxybenzoic acids | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1992-05-19 | — | — | US | disclosed |
| EP-0472113-A1 | Pyrimidine derivatives and herbicidal compositions containing the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1992-02-26 | — | — | EP | disclosed |