Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | FLT3 | P36888 | 3/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 2/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8803198 | 0.81 | MEN1 (0.43) | MEN1KMT2ANPC1RAB9AHDAC6 | |
| SCHEMBL19592646 | 0.80 | NPC1 (0.66) | NPC1RAB9AIDO1EGFRPIK3CA | |
| SCHEMBL2729915 | 0.78 | FLT3 (0.79) | MEN1KMT2ANPC1RAB9AHDAC6 | |
| SCHEMBL6170605 | 0.78 | MEN1 (0.78) | MEN1KMT2ANPC1RAB9AHDAC6 | |
| SCHEMBL8802023 | 0.75 | PPARG (0.49) | MEN1KMT2APPARGIDO1KDM4E | |
| SCHEMBL6170489 | 0.73 | MEN1 (0.70) | MEN1KMT2ANPC1RAB9AHDAC6 | |
| SCHEMBL16412569 | 0.72 | KDM4E (0.54) | MEN1KMT2ATSHRPPARGKDM4E | |
| SCHEMBL20494370 | 0.72 | HSD17B10 (0.60) | MEN1KMT2ACYP1A2CYP2C9IDO1 | |
| SCHEMBL27669939 | 0.71 | KMT2A (0.55) | MEN1KMT2ANPC1RAB9AHDAC6 | |
| SCHEMBL7066259 | 0.71 | FLT3 (0.71) | MEN1KMT2ANPC1RAB9AHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0804416-A1 | HETEROCYCLIC COMPOUNDS, USEFUL AS ALLOSTERIC EFFECTORS AT MUSCARINIC RECEPTORS | SANKYO COMPANY LIMITED (JP) | 1997-11-05 | — | — | EP | disclosed |