Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 5/20 | 0.46 |
| ▸ | MAOA | P21397 | 3/20 | 0.46 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CCR3 | P51677 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8807223 | 0.91 | KMT2A (0.48) | KMT2AMAOBMAOAP2RY1MEN1 | |
| SCHEMBL8805035 | 0.91 | KMT2A (0.48) | KMT2AMAOBMAOAP2RY1MEN1 | |
| SCHEMBL8806034 | 0.91 | KMT2A (0.59) | KMT2AMAOBMAOAP2RY1MEN1 | |
| SCHEMBL8806115 | 0.90 | KMT2A (0.47) | KMT2AMAOBMAOAP2RY1MEN1 | |
| SCHEMBL8805456 | 0.90 | KMT2A (0.61) | KMT2AMAOBMAOAP2RY1MEN1 | |
| SCHEMBL8804783 | 0.90 | KMT2A (0.61) | KMT2AMAOBMAOAP2RY1MEN1 | |
| SCHEMBL8803651 | 0.90 | KMT2A (0.61) | KMT2AMAOBMAOAP2RY1MEN1 | |
| SCHEMBL8803907 | 0.90 | KMT2A (0.61) | KMT2AMAOBMAOAP2RY1MEN1 | |
| SCHEMBL8802406 | 0.87 | MAOB (0.52) | KMT2AMAOBMAOAP2RY1CCR3 | |
| SCHEMBL8803605 | 0.87 | P2RY1 (0.45) | KMT2AMAOBMAOAP2RY1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625507-B1 | Urea derivatives and their use as acat inhibitors | NISSHIN FLOUR MILLING CO (JP) | 1997-07-23 | — | — | EP | disclosed |
| US-5621010-A | ANTIHYPERCHOLESTEROLEMIA AND ANTIATHEROSCLEROSIS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-04-15 | — | — | US | disclosed |
| EP-0625507-A2 | Urea derivatives and their use as acat inhibitors | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1994-11-23 | — | — | EP | disclosed |