Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8805866 | 0.87 | HTR1D (0.63) | HTR1DHTR1B | |
| SCHEMBL7475077 | 0.86 | HTR1D (1.00) | HTR1DHTR1B | |
| SCHEMBL8661705 | 0.83 | HTR1D (0.54) | HTR1DHTR1B | |
| SCHEMBL7476366 | 0.81 | HTR1D (1.00) | HTR1DHTR1B | |
| Oxalic Acid SCHEMBL8660714 | 0.79 | HTR1D (0.67) | HTR1DHTR1B | |
| SCHEMBL7485895 | 0.79 | HTR1D (0.86) | HTR1DHTR1B | |
| SCHEMBL7485900 | 0.79 | HTR1D (0.86) | HTR1DHTR1B | |
| SCHEMBL7474686 | 0.78 | HTR1D (0.95) | HTR1DHTR1B | |
| SCHEMBL7476583 | 0.78 | HTR1D (0.84) | HTR1DHTR1B | |
| SCHEMBL8664693 | 0.78 | HTR1D (0.72) | HTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0759918-A1 | PIPERAZINE, PIPERIDINE AND TETRAHYDROPYRIDINE DERIVATIVES OF INDOL-3-YLALKYL AS 5-HT1D-ALPHA AGONISTS | MERCK SHARP & DOHME LTD. (GB) | 1997-03-05 | — | — | EP | claimed |
| WO-1995032196-A1 | PIPERAZINE, PIPERIDINE AND TETRAHYDROPYRIDINE DERIVATIVES OF INDOL-3-YLALKYL AS 5-HT1D-ALPHA AGONISTS | MERCK SHARP & DOHME LIMITED (GB) | 1995-11-30 | — | — | WO | claimed |
| EP-0759918-A1 | PIPERAZINE, PIPERIDINE AND TETRAHYDROPYRIDINE DERIVATIVES OF INDOL-3-YLALKYL AS 5-HT1D-ALPHA AGONISTS | MERCK SHARP & DOHME LTD. (GB) | 1997-03-05 | — | — | EP | disclosed |
| WO-1995032196-A1 | PIPERAZINE, PIPERIDINE AND TETRAHYDROPYRIDINE DERIVATIVES OF INDOL-3-YLALKYL AS 5-HT1D-ALPHA AGONISTS | MERCK SHARP & DOHME LIMITED (GB) | 1995-11-30 | — | — | WO | disclosed |