Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.55 |
| ▸ | MAOA | P21397 | 5/20 | 0.55 |
| ▸ | CCR3 | P51677 | 4/20 | 0.49 |
| ▸ | ACHE | P22303 | 3/20 | 0.49 |
| ▸ | BCHE | P06276 | 2/20 | 0.45 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8803034 | 0.95 | MAOB (0.61) | MAOBMAOACCR3ACHEBCHE | |
| SCHEMBL8805057 | 0.90 | MAOB (0.69) | MAOBMAOACCR3ACHEBCHE | |
| SCHEMBL8803222 | 0.88 | KMT2A (0.46) | MAOBMAOACCR3ACHEUSP30 | |
| SCHEMBL8806034 | 0.85 | KMT2A (0.59) | MAOBMAOAKDM4ENPC1KMT2A | |
| SCHEMBL8804835 | 0.85 | MAOB (0.58) | MAOBMAOACCR3ACHEKDM4E | |
| SCHEMBL8803651 | 0.85 | KMT2A (0.61) | MAOBMAOAKDM4ENPC1KMT2A | |
| SCHEMBL8804783 | 0.85 | KMT2A (0.61) | MAOBMAOAKDM4ENPC1KMT2A | |
| SCHEMBL8805456 | 0.85 | KMT2A (0.61) | MAOBMAOAKDM4ENPC1KMT2A | |
| SCHEMBL8803907 | 0.85 | KMT2A (0.61) | MAOBMAOAKDM4ENPC1KMT2A | |
| SCHEMBL8804067 | 0.84 | MAOB (0.61) | MAOBMAOACCR3ACHEKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625507-B1 | Urea derivatives and their use as acat inhibitors | NISSHIN FLOUR MILLING CO (JP) | 1997-07-23 | — | — | EP | disclosed |
| US-5621010-A | ANTIHYPERCHOLESTEROLEMIA AND ANTIATHEROSCLEROSIS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-04-15 | — | — | US | disclosed |
| EP-0625507-A2 | Urea derivatives and their use as acat inhibitors | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1994-11-23 | — | — | EP | disclosed |