Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 6/20 | 0.70 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8411072 | 0.95 | PTGIR (0.78) | PTGIRSIGMAR1HTR1AADRA1A | |
| SCHEMBL8411099 | 0.89 | PTGIR (0.69) | PTGIRSIGMAR1HTR1AADRA1A | |
| SCHEMBL8520475 | 0.89 | PTGIR (0.70) | PTGIRSIGMAR1HTR1A | |
| SCHEMBL8410718 | 0.88 | PTGIR (0.90) | PTGIRSIGMAR1HTR1AADRA1A | |
| SCHEMBL8411068 | 0.82 | PTGIR (1.00) | PTGIR | |
| SCHEMBL8520473 | 0.78 | PTGIR (0.89) | PTGIR | |
| SCHEMBL8410884 | 0.77 | PTGIR (0.64) | PTGIR | |
| SCHEMBL8411096 | 0.77 | PTGIR (0.90) | PTGIR | |
| SCHEMBL8808628 | 0.77 | PTGIR (0.50) | PTGIRSIGMAR1 | |
| SCHEMBL8808959 | 0.75 | PTGIR (0.47) | PTGIRSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0548949-B1 | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO (JP) | 1997-09-17 | — | — | EP | claimed |
| EP-0548949-A2 | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-06-30 | — | — | EP | claimed |
| EP-0548949-B1 | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO (JP) | 1997-09-17 | — | — | EP | disclosed |
| US-5589496-A | Fused benzeneoxyacetic acid derivatives which have PGI2 receptor agonist activity | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-12-31 | — | — | US | disclosed |
| EP-0548949-A2 | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-06-30 | — | — | EP | disclosed |