⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11169234 | 0.76 | — | — | |
| SCHEMBL530977 | 0.70 | — | — | |
| SCHEMBL14997322 | 0.69 | — | — | |
| SCHEMBL6506795 | 0.69 | — | — | |
| SCHEMBL856278 | 0.69 | — | — | |
| SCHEMBL7158083 | 0.67 | — | — | |
| SCHEMBL20344873 | 0.67 | — | — | |
| SCHEMBL11523463 | 0.67 | — | — | |
| SCHEMBL20856328 | 0.67 | — | — | |
| SCHEMBL11011412 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792265-A1 | ENDOTHELIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-09-03 | — | — | EP | disclosed |
| EP-0055466-B1 | CEPHEM COMPOUNDS, PROCESSES FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR STARTING COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-05-06 | — | — | EP | disclosed |
| EP-0010667-B1 | CEPHAM COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESSES FOR THE PREPARATION THEREOF AND OF KNOWN CEPHEM COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-07-20 | — | — | EP | disclosed |
| EP-0046964-A2 | New cephem compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-03-10 | — | — | EP | disclosed |