⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10402631 | 0.77 | — | — | |
| SCHEMBL11295759 | 0.75 | — | — | |
| SCHEMBL11163217 | 0.71 | — | — | |
| SCHEMBL10949076 | 0.61 | — | — | |
| SCHEMBL10949078 | 0.61 | — | — | |
| SCHEMBL8104096 | 0.52 | — | — | |
| SCHEMBL8766874 | 0.52 | — | — | |
| SCHEMBL31553237 | 0.51 | HSD17B10 (0.33) | — | |
| SCHEMBL27473637 | 0.49 | — | — | |
| SCHEMBL14612064 | 0.49 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0232966-B1 | Process for the preparation of penem compounds and intermediates for this preparation | BEECHAM GROUP PLC (GB) | 1997-10-08 | — | — | EP | disclosed |
| EP-0232966-A1 | Process for the preparation of penem compounds and intermediates for this preparation | BEECHAM GROUP PLC (GB) | 1987-08-19 | — | — | EP | disclosed |