Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 16/20 | 0.83 |
| ▸ | HTR2B | P41595 | 16/20 | 0.83 |
| ▸ | HTR2A | P28223 | 12/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8810691 | 0.99 | HTR2C (0.81) | HTR2CHTR2BHTR2A | |
| SCHEMBL8810427 | 0.92 | HTR2C (0.77) | HTR2CHTR2BHTR2A | |
| Hydrochloric Acid SCHEMBL8811365 | 0.91 | HTR2C (0.76) | HTR2CHTR2BHTR2A | |
| Hydrochloric Acid SCHEMBL8809485 | 0.91 | HTR2C (0.76) | HTR2CHTR2BHTR2A | |
| Hydrochloric Acid SCHEMBL8814256 | 0.91 | HTR2C (0.89) | HTR2CHTR2BHTR2A | |
| SCHEMBL8810702 | 0.89 | HTR2C (0.72) | HTR2CHTR2BHTR2A | |
| Hydrochloric Acid SCHEMBL8811821 | 0.88 | HTR2C (0.78) | HTR2CHTR2BHTR2A | |
| SCHEMBL8813479 | 0.88 | HTR2C (1.00) | HTR2CHTR2BHTR2A | |
| SCHEMBL8809484 | 0.88 | HTR2C (0.80) | HTR2CHTR2BHTR2A | |
| Hydrochloric Acid SCHEMBL8809920 | 0.88 | HTR2C (0.71) | HTR2CHTR2BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997000872-A1 | 1,3,8-TRIAZA- AND 3,8-DIAZA-1-OXASPIRO(4,5)DECANE DERIVATIVES | F.HOFFMANN-LA ROCHE AG (CH) | 1997-01-09 | — | — | WO | disclosed |