Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 9/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 3/20 | 0.41 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8788369 | 0.85 | BCHE (0.53) | KMT2AMEN1BCHEACHENOX1 | |
| SCHEMBL8805014 | 0.79 | BCHE (0.53) | HDAC6HDAC1HDAC8KMT2AMEN1 | |
| SCHEMBL25388003 | 0.74 | NOX1 (0.68) | HDAC6HDAC1HDAC8KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL8805018 | 0.74 | BCHE (0.53) | HDAC6HDAC1HDAC8KMT2AMEN1 | |
| SCHEMBL9474423 | 0.70 | BCHE (0.49) | HDAC6HDAC1HDAC8KMT2AMEN1 | |
| SCHEMBL9568253 | 0.70 | KMT2A (0.55) | HDAC6HDAC1HDAC8KMT2AMEN1 | |
| SCHEMBL9475584 | 0.69 | NOX1 (0.53) | HDAC6HDAC1HDAC8KMT2AMEN1 | |
| SCHEMBL21693081 | 0.67 | KMT2A (0.51) | HDAC6HDAC1HDAC8KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL2266107 | 0.66 | BCHE (0.66) | BCHEACHENOX1 | |
| Hydrochloric Acid SCHEMBL2363423 | 0.66 | BCHE (0.66) | BCHEACHENOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0527298-B1 | Process for the preparation of pipazethate | ASTA MEDICA AG (DE) | 1997-07-30 | — | — | EP | claimed |
| EP-0527298-A1 | Process for the preparation of pipazethate | ASTA Medica Aktiengesellschaft (DE) | 1993-02-17 | — | — | EP | claimed |