Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 9/20 | 0.81 |
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | PIM1 | P11309 | 1/20 | 0.51 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.51 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | TTR | P02766 | 1/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8685984 | 1.00 | PARP1 (0.81) | PARP1LMNAMAPTALDH1A1NPSR1 | |
| SCHEMBL1248861 | 0.89 | PARP1 (0.83) | PARP1LMNAMAPTALDH1A1NPSR1 | |
| SCHEMBL1248859 | 0.89 | PARP1 (0.83) | PARP1LMNAMAPTALDH1A1NPSR1 | |
| SCHEMBL12891974 | 0.89 | PARP1 (0.83) | PARP1LMNAMAPTALDH1A1NPSR1 | |
| SCHEMBL8809776 | 0.89 | PARP1 (0.64) | PARP1LMNAMAPTALDH1A1NPSR1 | |
| SCHEMBL8690727 | 0.89 | PARP1 (0.79) | PARP1LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL8812784 | 0.89 | PARP1 (0.79) | PARP1LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL8690307 | 0.88 | PARP1 (0.74) | PARP1LMNAMAPTMEN1KMT2A | |
| SCHEMBL8810629 | 0.88 | PARP1 (0.74) | PARP1LMNAMAPTMEN1KMT2A | |
| SCHEMBL8809167 | 0.88 | PARP1 (0.62) | PARP1LMNAMAPTALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0780389-A1 | Thiazolidinedione derivatives, process for their preparation and pharmaceutical compositions containing them | TOBISHI PHARMACEUTICAL CO., LTD. (JP) | 1997-06-25 | — | — | EP | disclosed |