Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 15/20 | 0.63 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | DRD3 | P35462 | 2/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8811199 | 0.89 | PTGIR (0.63) | PTGIRPTGDRSIGMAR1 | |
| SCHEMBL8414286 | 0.86 | PTGIR (0.68) | PTGIRPTGDR | |
| SCHEMBL8414284 | 0.86 | PTGIR (0.87) | PTGIRPTGDR | |
| SCHEMBL8813545 | 0.80 | PTGIR (0.54) | PTGIRCYP19A1PTGDRDRD2DRD3 | |
| SCHEMBL8410742 | 0.77 | PTGIR (0.77) | PTGIRPTGDR | |
| SCHEMBL8410741 | 0.77 | PTGIR (1.00) | PTGIRPTGDR | |
| SCHEMBL8413473 | 0.76 | PTGIR (0.76) | PTGIRPTGDR | |
| SCHEMBL8808641 | 0.76 | PTGIR (0.75) | PTGIRPTGDR | |
| SCHEMBL8410969 | 0.76 | PTGIR (0.86) | PTGIRPTGDR | |
| SCHEMBL8519034 | 0.75 | PTGIR (0.68) | PTGIRPTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0548949-B1 | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO (JP) | 1997-09-17 | — | — | EP | disclosed |