Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.50 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | FDPS | P14324 | 4/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.37 |
| ▸ | PRKCG | P05129 | 1/20 | 0.37 |
| ▸ | PRKCB | P05771 | 1/20 | 0.37 |
| ▸ | PRKCA | P17252 | 1/20 | 0.37 |
| ▸ | PRKCH | P24723 | 1/20 | 0.37 |
| ▸ | PRKCI | P41743 | 1/20 | 0.37 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.37 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.37 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.37 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.37 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7700058 | 0.98 | ACE2 (0.53) | TP53ACE2S1PR2S1PR1S1PR3 | |
| SCHEMBL3426179 | 0.98 | ACE2 (0.53) | TP53ACE2S1PR2S1PR1S1PR3 | |
| SCHEMBL8813307 | 0.98 | ACE2 (0.53) | TP53ACE2S1PR2S1PR1S1PR3 | |
| SCHEMBL8811502 | 0.94 | TP53 (0.45) | TP53ACE2S1PR2S1PR1S1PR3 | |
| SCHEMBL11427268 | 0.87 | EPHX2 (0.52) | TP53ACE2EPHX2FFAR1LMNA | |
| SCHEMBL8810924 | 0.85 | TP53 (0.45) | TP53ACE2S1PR2S1PR1S1PR3 | |
| SCHEMBL5637992 | 0.85 | TSHR (0.44) | TP53ACE2S1PR2S1PR1S1PR3 | |
| SCHEMBL14915359 | 0.85 | APP (0.42) | TP53ACE2S1PR2S1PR1S1PR3 | |
| SCHEMBL28530390 | 0.85 | APP (0.42) | TP53ACE2S1PR2S1PR1S1PR3 | |
| SCHEMBL8810602 | 0.83 | TP53 (0.44) | TP53ACE2S1PR2S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691319-A | ANTICARCINOGENIC AGENTS | SANKYO COMPANY, LIMITED (JP) | 1997-11-25 | — | — | US | disclosed |
| EP-0536936-B1 | Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use | SANKYO CO (JP) | 1996-08-14 | — | — | EP | disclosed |
| EP-0536936-A1 | Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use | Sankyo Company Limited (JP) | 1993-04-14 | — | — | EP | disclosed |