SCHEMBL8812178

CC[C@H](C)[C@@H](CN(CC(=O)N[C@@H](CCSC)C(=O)O)Cc1cccc2ccccc12)NC(=O)[C@H](N)c1c[nH]cn1.CC[C@H](C)[C@@H](CN(CC(=O)N[C@@H](CCSC)C(=O)OC)Cc1cccc2ccccc12)NC(=O)[C@H](N)c1c[nH]cn1

nearest known ligand 0.60

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	FNTA	P49354	14/20	0.60

▸	FNTB	P49356	14/20	0.60

▸	CTSD	P07339	2/20	0.36

▸	MME	P08473	1/20	0.36

▸	ACE	P12821	1/20	0.36

▸	CPA1	P15085	1/20	0.36

▸	ACE2	Q9BYF1	1/20	0.36

▸	APOBEC3G	Q9HC16	1/20	0.35

▸	CYP2C9	P11712	1/20	0.34

▸	TSHR	P16473	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL8812175	1.00	FNTA (0.60)	FNTAFNTBCTSDMMEACE
SCHEMBL7632039	0.98	FNTA (0.57)	FNTAFNTBCTSDAPOBEC3GCYP2C9
SCHEMBL7985626	0.98	FNTA (0.57)	FNTAFNTBCTSDAPOBEC3GCYP2C9
SCHEMBL7620079	0.98	FNTA (0.57)	FNTAFNTBCTSDAPOBEC3GCYP2C9
SCHEMBL7623036	0.96	FNTA (0.65)	FNTAFNTBMMEACECPA1
SCHEMBL7629076	0.96	FNTA (0.65)	FNTAFNTBMMEACECPA1
SCHEMBL7623044	0.96	FNTA (0.65)	FNTAFNTBMMEACECPA1
SCHEMBL8810938	0.95	FNTA (0.58)	FNTAFNTBCTSDMMEACE
SCHEMBL6056549	0.88	FNTA (0.56)	FNTAFNTBCTSDAPOBEC3G
SCHEMBL6056551	0.88	FNTA (0.56)	FNTAFNTBCTSDAPOBEC3G

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-1997001275-A1	COMBINATIONS OF INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE	MERCK & CO., INC. (US)	1997-01-16	—	—	WO	claimed