Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL6ST | P40189 | 5/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | IDH1 | O75874 | 9/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7787910 | 1.00 | IL6ST (0.64) | IL6STHSD17B10STAT3PPARANAAA | |
| SCHEMBL8812238 | 1.00 | IL6ST (0.64) | IL6STHSD17B10STAT3PPARANAAA | |
| SCHEMBL17418485 | 0.90 | IL6ST (0.64) | IL6STHSD17B10STAT3NAAAIDH1 | |
| SCHEMBL20099031 | 0.90 | IL6ST (0.64) | IL6STHSD17B10STAT3NAAAIDH1 | |
| SCHEMBL17418481 | 0.90 | IL6ST (0.64) | IL6STHSD17B10STAT3NAAAIDH1 | |
| SCHEMBL20132809 | 0.88 | IL6ST (0.50) | IL6STSTAT3IDH1PIK3CD | |
| SCHEMBL20132776 | 0.88 | IL6ST (0.50) | IL6STSTAT3IDH1PIK3CD | |
| SCHEMBL18174256 | 0.88 | IL6ST (0.50) | IL6STSTAT3IDH1PIK3CD | |
| SCHEMBL18174279 | 0.88 | IL6ST (0.50) | IL6STSTAT3IDH1PIK3CD | |
| SCHEMBL18174223 | 0.88 | IL6ST (0.50) | IL6STSTAT3IDH1PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5672586-A | Herpes ribonucleotide reductase inhibitors | BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH, INC. (CA) | 1997-09-30 | — | — | US | disclosed |