Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR2 | P21452 | 14/20 | 0.62 |
| ▸ | TACR1 | P25103 | 14/20 | 0.62 |
| ▸ | TACR3 | P29371 | 1/20 | 0.52 |
| ▸ | HRH1 | P35367 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8808304 | 0.89 | TACR2 (0.77) | TACR2TACR1TACR3HRH1 | |
| SCHEMBL8807069 | 0.87 | TACR2 (0.80) | TACR2TACR1TACR3HRH1 | |
| SCHEMBL8810353 | 0.84 | TACR2 (0.81) | TACR2TACR1TACR3HRH1 | |
| SCHEMBL8808621 | 0.83 | TACR2 (0.80) | TACR2TACR1TACR3HRH1 | |
| SCHEMBL8809673 | 0.82 | TACR2 (0.69) | TACR2TACR1TACR3HRH1 | |
| SCHEMBL8809790 | 0.82 | TACR2 (0.66) | TACR2TACR1TACR3HRH1 | |
| SCHEMBL8808230 | 0.82 | TACR2 (0.69) | TACR2TACR1TACR3HRH1 | |
| SCHEMBL8808635 | 0.81 | TACR2 (0.81) | TACR2TACR1TACR3HRH1 | |
| SCHEMBL7958373 | 0.80 | TACR2 (0.52) | TACR2TACR1TACR3HRH1 | |
| SCHEMBL8808966 | 0.79 | TACR2 (0.80) | TACR2TACR1TACR3HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696280-B1 | SUBSTITUTED PYRROLIDIN-3-YL-ALKYL-PIPERIDINES USEFUL AS TACHYKININ ANTAGONISTS | MERRELL PHARMA INC (US) | 1997-09-24 | — | — | EP | claimed |