SCHEMBL8812959

CC[C@H](C)[C@@H](CN(CC(=O)N[C@@H](CCSC)C(=O)O)Cc1ccccc1)NC(=O)Cn1cnnn1.CC[C@H](C)[C@@H](CN(CC(=O)N[C@@H](CCSC)C(=O)OC)Cc1ccccc1)NC(=O)Cn1cnnn1

nearest known ligand 0.57

Predicted protein targets (top 5)

	gene	UniProt	supporting neighbours	confidence
▸	FNTA	P49354	15/20	0.57

▸	FNTB	P49356	15/20	0.57

▸	PGGT1B	P53609	2/20	0.38

▸	TSHR	P16473	1/20	0.37

▸	L3MBTL1	Q9Y468	1/20	0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL8812953	1.00	FNTA (0.57)	FNTAFNTBPGGT1BTSHRL3MBTL1
SCHEMBL6056574	0.98	FNTA (0.55)	FNTAFNTBPGGT1BTSHRL3MBTL1
SCHEMBL6056575	0.98	FNTA (0.55)	FNTAFNTBPGGT1BTSHRL3MBTL1
SCHEMBL6056405	0.96	FNTA (0.61)	FNTAFNTBPGGT1B
SCHEMBL6056414	0.96	FNTA (0.61)	FNTAFNTBPGGT1B
SCHEMBL8812487	0.92	FNTA (0.49)	FNTAFNTBPGGT1B
SCHEMBL8812497	0.92	FNTA (0.49)	FNTAFNTBPGGT1B
SCHEMBL9070336	0.80	FNTA (0.63)	FNTAFNTB
SCHEMBL9070335	0.80	FNTA (0.63)	FNTAFNTB
SCHEMBL6056530	0.79	FNTA (0.52)	FNTAFNTBPGGT1BTSHRL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-0773942-A1	4-INDOLE DERIVATIVES AS SEROTONIN AGONISTS AND ANTAGONISTS	PFIZER INC. (US)	1997-05-21	—	—	EP	disclosed
WO-1997001275-A1	COMBINATIONS OF INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE	MERCK & CO., INC. (US)	1997-01-16	—	—	WO	disclosed
WO-1996003400-A1	4-INDOLE DERIVATIVES AS SEROTONIN AGONISTS AND ANTAGONISTS	PFIZER INC. (US)	1996-02-08	—	—	WO	disclosed