Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.70 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | POLA1 | P09884 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | DGKA | P23743 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10958389 | 1.00 | TSHR (0.70) | TSHRLMNAALDH1A1KMT2ARECQL | |
| SCHEMBL29195604 | 0.97 | TSHR (0.67) | TSHRLMNAALDH1A1KMT2ARECQL | |
| SCHEMBL28971642 | 0.95 | TSHR (0.70) | TSHRLMNAALDH1A1KMT2ARECQL | |
| SCHEMBL494299 | 0.92 | TSHR (0.82) | TSHRLMNAALDH1A1KMT2ARECQL | |
| SCHEMBL494114 | 0.92 | TSHR (0.82) | TSHRLMNAALDH1A1KMT2ARECQL | |
| SCHEMBL3503395 | 0.92 | TSHR (0.82) | TSHRLMNAALDH1A1KMT2ARECQL | |
| SCHEMBL3502791 | 0.92 | TSHR (0.82) | TSHRLMNAALDH1A1KMT2ARECQL | |
| SCHEMBL118000 | 0.92 | TSHR (0.82) | TSHRLMNAALDH1A1KMT2ARECQL | |
| SCHEMBL1286873 | 0.92 | TSHR (0.82) | TSHRLMNAALDH1A1KMT2ARECQL | |
| SCHEMBL3501872 | 0.92 | TSHR (0.82) | TSHRLMNAALDH1A1KMT2ARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691319-A | ANTICARCINOGENIC AGENTS | SANKYO COMPANY, LIMITED (JP) | 1997-11-25 | — | — | US | disclosed |
| EP-0536936-B1 | Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use | SANKYO CO (JP) | 1996-08-14 | — | — | EP | disclosed |
| EP-0536936-A1 | Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use | Sankyo Company Limited (JP) | 1993-04-14 | — | — | EP | disclosed |