Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 4/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA7 | P43166 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | TACR1 | P25103 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10127440 | 0.86 | TSHR (0.50) | TSHRCA1CA2CA7CA9 | |
| SCHEMBL28973808 | 0.83 | TSHR (0.56) | TSHRCA1CA2CA7CA9 | |
| SCHEMBL14453899 | 0.83 | TSHR (0.61) | TSHRCA1CA2CA7CA9 | |
| SCHEMBL172650 | 0.82 | TSHR (0.50) | TSHRCA1CA2CA7CA9 | |
| SCHEMBL29516747 | 0.82 | TSHR (0.50) | TSHRCA1CA2CA7CA9 | |
| SCHEMBL13246484 | 0.82 | TSHR (0.50) | TSHRCA1CA2CA7CA9 | |
| SCHEMBL13464527 | 0.82 | TSHR (0.50) | TSHRCA1CA2CA7CA9 | |
| SCHEMBL1195445 | 0.81 | CA1 (0.50) | TSHRCA1CA2CA7CA9 | |
| SCHEMBL27622931 | 0.81 | TSHR (0.48) | TSHRCA1CA2CA7CA9 | |
| SCHEMBL27622929 | 0.81 | TSHR (0.48) | TSHRCA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997011936-A1 | PREPARATION OF CARBOXYALKYL DERIVATIVES | MERCK & CO., INC. (US) | 1997-04-03 | — | — | WO | disclosed |