SCHEMBL8814130

SCHEMBL8814130

Ic1ccccc1OC1CCCC1

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MCHR1 Q99705 2/20 0.42
CARM1 Q86X55 2/20 0.41
PRMT1 Q99873 2/20 0.41
HRH1 P35367 2/20 0.41
PDE4A P27815 4/20 0.40
PDE4B Q07343 2/20 0.40
PDE4C Q08493 2/20 0.40
PDE4D Q08499 2/20 0.40
PDE5A O76074 1/20 0.40
MRGPRX1 Q96LB2 1/20 0.40
SCD O00767 1/20 0.38
CSNK2A1 P68400 2/20 0.38
SLC6A2 P23975 2/20 0.38
SLC6A3 Q01959 2/20 0.38
HTR1A P08908 1/20 0.38
SLC6A4 P31645 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22181087 0.98 MCHR1 (0.45) MCHR1CARM1PRMT1HRH1PDE4A
SCHEMBL31371822 0.96 HRH1 (0.41) MCHR1CARM1PRMT1HRH1PDE4A
SCHEMBL14915542 0.91 HRH1 (0.43) MCHR1HRH1SCDSLC6A2SLC6A3
SCHEMBL5344402 0.84 MCHR1 (0.49) MCHR1CARM1PRMT1HRH1PDE4A
SCHEMBL674990 0.82 KAT2B (0.53) HRH1PDE4APDE4BPDE4CPDE4D
SCHEMBL2242864 0.82 MCHR1 (0.51) MCHR1CARM1PRMT1HRH1PDE4A
SCHEMBL28425007 0.81 MCHR1 (0.47) MCHR1CARM1PRMT1HRH1PDE4A
SCHEMBL17924661 0.80 MCHR1 (0.44) MCHR1CARM1PRMT1HRH1PDE4A
SCHEMBL15565053 0.80 MCHR1 (0.44) MCHR1CARM1PRMT1PDE4APDE4B
SCHEMBL26519424 0.78 PTPRF (0.34) HRH1PDE4BSCDSLC6A2SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5620677-A CONTRAST AGENTS IN DIAGNOSTIC RADIOLOGY STERLING WINTHROP INC. (US) 1997-04-15 US claimed
US-5607660-A X-RAY CONTRAST AGENTS FOR INTESTINES STERLING WINTHROP INC. (US) 1997-03-04 US claimed
US-5531979-A X-RAY CONTRAST COMPOSITION STERLING WINTHROP INC. (US) 1996-07-02 US claimed
EP-0609586-A2 Compositions of iodophenoxy alkanes and iodophenyl ethers for visualization of the gastrointestinal tract NYCOMED IMAGING AS (NO) 1994-08-10 EP claimed
EP-0609587-A2 Compositions of iodophenoxy alkanes and iodophenyl ethers in film-forming materials for visualization of the gastrointestinal tract NYCOMED IMAGING AS (NO) 1994-08-10 EP claimed
US-5326553-A Compositions of iodophenoxy alkanes and iodophenyl ethers in film-forming materials for visualization of the gastrointestinal tract STERLING WINTHROP INC. (US) 1994-07-05 US claimed
US-5316755-A AQUEOUS X-RAY CONTRAST COMPOSITION FOR ORAL OR RECTAL ADMINISTRATION STERLING WINTHROP INC. (US) 1994-05-31 US claimed
US-5620677-A CONTRAST AGENTS IN DIAGNOSTIC RADIOLOGY STERLING WINTHROP INC. (US) 1997-04-15 US disclosed
US-5607660-A X-RAY CONTRAST AGENTS FOR INTESTINES STERLING WINTHROP INC. (US) 1997-03-04 US disclosed
EP-0756497-A1 X-RAY CONTRAST COMPOSITIONS CONTAINING PHARMACEUTICALLY ACCEPTABLE CLAYS NYCOMED IMAGING AS (NO) 1997-02-05 EP disclosed
EP-0746339-A1 X-RAY CONTRAST COMPOSITIONS CONTAINING CELLULOSE DERIVATIVES NYCOMED IMAGING AS (NO) 1996-12-11 EP disclosed
US-5531979-A X-RAY CONTRAST COMPOSITION STERLING WINTHROP INC. (US) 1996-07-02 US disclosed
WO-1995028969-A1 X-RAY CONTRAST COMPOSITIONS CONTAINING PHARMACEUTICALLY ACCEPTABLE CLAYS NYCOMED IMAGING AS (NO) 1995-11-02 WO disclosed
WO-1995022995-A1 X-RAY CONTRAST COMPOSITIONS CONTAINING CELLULOSE DERIVATIVES NYCOMED IMAGING A/S (NO) 1995-08-31 WO disclosed
EP-0609586-A2 Compositions of iodophenoxy alkanes and iodophenyl ethers for visualization of the gastrointestinal tract NYCOMED IMAGING AS (NO) 1994-08-10 EP disclosed
EP-0609587-A2 Compositions of iodophenoxy alkanes and iodophenyl ethers in film-forming materials for visualization of the gastrointestinal tract NYCOMED IMAGING AS (NO) 1994-08-10 EP disclosed
US-5326553-A Compositions of iodophenoxy alkanes and iodophenyl ethers in film-forming materials for visualization of the gastrointestinal tract STERLING WINTHROP INC. (US) 1994-07-05 US disclosed
US-5316755-A AQUEOUS X-RAY CONTRAST COMPOSITION FOR ORAL OR RECTAL ADMINISTRATION STERLING WINTHROP INC. (US) 1994-05-31 US disclosed