Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.35 |
| ▸ | POLRMT | O00411 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30269951 | 0.95 | TMPRSS2 (0.40) | TMPRSS2POLRMT | |
| SCHEMBL24149141 | 0.95 | TMPRSS2 (0.40) | TMPRSS2POLRMT | |
| SCHEMBL882033 | 0.90 | TMPRSS2 (0.36) | TMPRSS2POLRMT | |
| SCHEMBL30269866 | 0.90 | TMPRSS2 (0.38) | TMPRSS2 | |
| SCHEMBL24148992 | 0.90 | TMPRSS2 (0.38) | TMPRSS2 | |
| SCHEMBL30472852 | 0.89 | TMPRSS2 (0.38) | TMPRSS2POLRMT | |
| SCHEMBL24149187 | 0.89 | TMPRSS2 (0.37) | TMPRSS2POLRMT | |
| SCHEMBL30269874 | 0.89 | TMPRSS2 (0.37) | TMPRSS2POLRMT | |
| SCHEMBL24149813 | 0.88 | TMPRSS2 (0.32) | TMPRSS2 | |
| SCHEMBL25012547 | 0.88 | TMPRSS2 (0.32) | TMPRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012039787-A1 | 2' -FLUORO SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT | GILEAD SCIENCES, INC. (US) | 2012-03-29 | — | — | WO | disclosed |
| WO-2012039791-A1 | 2' -FLUORO SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT | GILEAD SCIENCES, INC. (US) | 2012-03-29 | — | — | WO | disclosed |