Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKAR | P32238 | 18/20 | 0.78 |
| ▸ | CCKBR | P32239 | 15/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8806774 | 0.92 | CCKAR (0.81) | CCKARCCKBRALDH1A1 | |
| SCHEMBL8817635 | 0.90 | CCKAR (0.78) | CCKARCCKBRALDH1A1 | |
| SCHEMBL8804848 | 0.89 | CCKAR (0.77) | CCKARCCKBRALDH1A1 | |
| SCHEMBL8810636 | 0.88 | CCKAR (1.00) | CCKARCCKBR | |
| SCHEMBL8812659 | 0.86 | CCKAR (0.72) | CCKARCCKBRALDH1A1 | |
| SCHEMBL8805505 | 0.85 | CCKAR (0.71) | CCKARCCKBRALDH1A1 | |
| SCHEMBL8804292 | 0.84 | CCKAR (0.85) | CCKARCCKBR | |
| SCHEMBL8812239 | 0.84 | CCKAR (0.71) | CCKARCCKBR | |
| SCHEMBL8815285 | 0.84 | CCKAR (0.69) | CCKARCCKBRALDH1A1 | |
| SCHEMBL8806839 | 0.83 | CCKAR (0.81) | CCKARCCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755384-A1 | CCK OR GASTRIN MODULATING 1,5 BENZODIAZEPINES DERIVATIVES | GLAXO WELLCOME INC. (US) | 1997-01-29 | — | — | EP | disclosed |
| WO-1995028391-A1 | CCK OR GASTRIN MODULATING 1,5 BENZODIAZEPINES DERIVATIVES | GLAXO WELLCOME INC. (US) | 1995-10-26 | — | — | WO | disclosed |