Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.52 |
| ▸ | PIM1 | P11309 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 1/20 | 0.52 |
| ▸ | LTK | P29376 | 1/20 | 0.52 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.52 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 7/20 | 0.46 |
| ▸ | CA9 | Q16790 | 7/20 | 0.46 |
| ▸ | CA1 | P00915 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8818181 | 0.85 | IDO1 (0.59) | CHEK1PIM1IDO1LTKLIMK1 | |
| SCHEMBL8818171 | 0.85 | IDO1 (0.59) | CHEK1PIM1IDO1LTKLIMK1 | |
| SCHEMBL30133461 | 0.84 | MEN1 (0.48) | IDO1CA2CA9CA1MAPT | |
| SCHEMBL8439504 | 0.84 | MEN1 (0.48) | IDO1CA2CA9CA1MAPT | |
| SCHEMBL8814720 | 0.84 | IDO1 (0.59) | CHEK1PIM1IDO1LTKLIMK1 | |
| SCHEMBL21580219 | 0.84 | MEN1 (0.48) | IDO1CA2CA9CA1MAPT | |
| SCHEMBL8818168 | 0.83 | IDO1 (0.54) | CHEK1PIM1IDO1LTKLIMK1 | |
| SCHEMBL8818174 | 0.83 | IDO1 (0.54) | CHEK1PIM1IDO1LTKLIMK1 | |
| SCHEMBL18073621 | 0.80 | CA12 (0.57) | IDO1CA2CA9CA1MAPT | |
| SCHEMBL8818039 | 0.80 | CHEK1 (0.50) | CHEK1PIM1IDO1LTKLIMK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997016194-A1 | NAPHTHYLAZO INHIBITION OF AMYLOIDOSIS | WARNER-LAMBERT COMPANY (US) | 1997-05-09 | — | — | WO | claimed |