Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 13/20 | 0.57 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GALR3 | O60755 | 1/20 | 0.43 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PHGDH | O43175 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL881387 | 0.83 | PTGER4 (0.80) | PTGER4PTGER2KDM4EMAPTPHGDH | |
| SCHEMBL26403801 | 0.82 | PTGER4 (0.73) | PTGER4PTGER2MAPK14SMN1; SMN2 | |
| SCHEMBL876398 | 0.81 | KDM4E (0.68) | PTGER4PTGER2KDM4EMAPTCYP3A4 | |
| SCHEMBL15249919 | 0.81 | PTGER4 (0.71) | PTGER4PTGER2KDM4EMAPTCYP3A4 | |
| SCHEMBL24861734 | 0.78 | PTGER4 (0.73) | PTGER4PTGER2LMNAPHGDH | |
| SCHEMBL26420304 | 0.78 | PTGER4 (0.73) | PTGER4PTGER2LMNAPHGDH | |
| SCHEMBL15250012 | 0.76 | PTGER4 (0.69) | PTGER4PTGER2KDM4EMAPTCYP3A4 | |
| SCHEMBL15249947 | 0.75 | PTGER4 (0.71) | PTGER4PTGER2LMNASMN1; SMN2PHGDH | |
| SCHEMBL28701983 | 0.74 | PTGER4 (0.77) | PTGER4PTGER2PHGDH | |
| SCHEMBL28701981 | 0.74 | PTGER4 (0.77) | PTGER4PTGER2PHGDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012039972-A1 | PHARMACEUTICAL COMPOSITION | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2012-03-29 | — | — | WO | disclosed |