Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 10/20 | 0.68 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.55 |
| ▸ | PHGDH | O43175 | 9/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10122334 | 0.94 | PTGER4 (0.77) | PTGER4PTGER2PHGDHKDM4EMAPT | |
| SCHEMBL15249912 | 0.89 | PTGER4 (0.67) | PTGER4PTGER2PHGDHKDM4EMAPT | |
| SCHEMBL881393 | 0.88 | PTGER4 (0.72) | PTGER4PTGER2PHGDHKDM4EMAPT | |
| SCHEMBL881501 | 0.88 | PTGER4 (0.69) | PTGER4PTGER2PHGDHKDM4EMAPT | |
| SCHEMBL881409 | 0.87 | PTGER4 (0.79) | PTGER4PTGER2PHGDH | |
| SCHEMBL881499 | 0.86 | PTGER4 (0.69) | PTGER4PTGER2PHGDHKDM4EMAPT | |
| SCHEMBL15249966 | 0.86 | PTGER4 (0.67) | PTGER4PTGER2PHGDHKDM4EMAPT | |
| SCHEMBL881424 | 0.85 | PTGER4 (0.71) | PTGER4PTGER2PHGDHKDM4EMAPT | |
| SCHEMBL15249889 | 0.85 | PTGER4 (0.79) | PTGER4PTGER2PHGDH | |
| SCHEMBL881184 | 0.85 | PTGER4 (0.70) | PTGER4PTGER2PHGDHKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012039972-A1 | PHARMACEUTICAL COMPOSITION | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2012-03-29 | — | — | WO | disclosed |