Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 6/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PHGDH | O43175 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL881393 | 0.88 | PTGER4 (0.72) | PTGER4CYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL15249968 | 0.86 | PTGER4 (0.62) | PTGER4CYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL26416612 | 0.79 | PTGER4 (0.68) | PTGER4CYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL26416727 | 0.79 | PTGER4 (0.63) | PTGER4CYP1A2CYP2C9CYP2C19PTGER2 | |
| SCHEMBL26416614 | 0.79 | PTGER4 (0.57) | PTGER4CYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL24861754 | 0.77 | PTGER4 (0.58) | PTGER4PTGER2PHGDHACACB | |
| SCHEMBL15250004 | 0.77 | PTGER4 (0.60) | PTGER4CYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL881184 | 0.77 | PTGER4 (0.70) | PTGER4CYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL15249899 | 0.76 | PTGER4 (0.79) | PTGER4PTGER2PHGDH | |
| SCHEMBL24861773 | 0.76 | PTGER4 (0.75) | PTGER4PTGER2PHGDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012039972-A1 | PHARMACEUTICAL COMPOSITION | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2012-03-29 | — | — | WO | disclosed |