Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 9/20 | 0.47 |
| ▸ | RARA | P10276 | 2/20 | 0.47 |
| ▸ | RARG | P13631 | 1/20 | 0.47 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | GCGR | P47871 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8017398 | 0.91 | RARB (0.40) | RARBRARARARGCYP17A1CYP11B1 | |
| SCHEMBL8017395 | 0.91 | RARB (0.40) | RARBRARARARGCYP17A1CYP11B1 | |
| SCHEMBL10345128 | 0.90 | CYP17A1 (0.42) | RARBRARARARGCYP17A1CYP11B1 | |
| SCHEMBL3166812 | 0.90 | HRH3 (0.41) | RARBRARARARGCYP17A1CYP11B1 | |
| SCHEMBL3166825 | 0.90 | HRH3 (0.41) | RARBRARARARGCYP17A1CYP11B1 | |
| SCHEMBL8027605 | 0.89 | RARB (0.44) | RARBRARARARGGPR84MAOA | |
| SCHEMBL8027611 | 0.89 | RARB (0.44) | RARBRARARARGGPR84MAOA | |
| SCHEMBL10723919 | 0.89 | CYP17A1 (0.41) | RARBRARARARGCYP17A1CYP11B1 | |
| SCHEMBL10723905 | 0.89 | CYP17A1 (0.41) | RARBRARARARGCYP17A1CYP11B1 | |
| SCHEMBL7754624 | 0.89 | CYP3A4 (0.41) | MAOAMAOBCYP3A4CYP2C8CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-9143103-A | — | — | None | — | — | JP | disclosed |
| JP-H09143103-A | 4-(2-CYCLOHEXYL) ETHYL BIPHENYL DERIVATIVE | DAINIPPON INK & CHEM INC | 1997-06-03 | — | — | JP | disclosed |