Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 9/20 | 0.56 |
| ▸ | GAA | P10253 | 9/20 | 0.56 |
| ▸ | SI | P14410 | 9/20 | 0.56 |
| ▸ | MGAM2 | Q2M2H8 | 9/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 2/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.41 |
| ▸ | VSIR | Q9H7M9 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TNKS | O95271 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8816726 | 0.89 | MGAM (0.62) | MGAMGAASIMGAM2MAPK1 | |
| SCHEMBL8818707 | 0.88 | MGAM (0.51) | MGAMGAASIMGAM2MAPK1 | |
| SCHEMBL8818781 | 0.86 | MGAM (0.54) | MGAMGAASIMGAM2MAPK1 | |
| SCHEMBL8817500 | 0.86 | NPC1 (0.53) | MGAMGAASIMGAM2RAB9A | |
| SCHEMBL8816713 | 0.84 | MGAM (0.51) | MGAMGAASIMGAM2RAB9A | |
| SCHEMBL8817558 | 0.84 | MGAM (0.51) | MGAMGAASIMGAM2RAB9A | |
| Bromide SCHEMBL8818674 | 0.81 | MGAM (0.60) | MGAMGAASIMGAM2NR1I3 | |
| SCHEMBL6686102 | 0.81 | MGAM (0.62) | MGAMGAASIMGAM2MAPK1 | |
| SCHEMBL8816929 | 0.81 | PARP1 (0.51) | MGAMGAASIMGAM2RAB9A | |
| SCHEMBL8818832 | 0.80 | PARP1 (0.54) | MGAMGAASIMGAM2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997033873-A1 | METHODS OF TREATING OR PREVENTING INTERSTITIAL CYSTITIS | ELI LILLY AND COMPANY (US) | 1997-09-18 | — | — | WO | disclosed |
| WO-1997031635-A1 | METHODS OF TREATING OR PREVENTING SLEEP APNEA | ELI LILLY AND COMPANY (US) | 1997-09-04 | — | — | WO | disclosed |