Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 7/20 | 0.58 |
| ▸ | DHODH | Q02127 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | CBFB | Q13951 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MGAM | O43451 | 1/20 | 0.45 |
| ▸ | SI | P14410 | 1/20 | 0.45 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8818794 | 0.91 | PARP1 (0.56) | PARP1DHODHMAPTTP53ALDH1A1 | |
| SCHEMBL8818853 | 0.90 | PARP1 (0.58) | PARP1DHODHMAPTTP53ALDH1A1 | |
| SCHEMBL8817062 | 0.90 | PARP1 (0.55) | PARP1DHODHMAPTTP53ALDH1A1 | |
| SCHEMBL8816600 | 0.90 | PARP1 (0.55) | PARP1DHODHMAPTTP53ALDH1A1 | |
| SCHEMBL8818738 | 0.90 | PARP1 (0.55) | PARP1DHODHMAPTTP53ALDH1A1 | |
| SCHEMBL8891814 | 0.89 | PARP1 (0.57) | PARP1DHODHMAPTTP53ALDH1A1 | |
| SCHEMBL8814896 | 0.87 | PARP1 (0.53) | PARP1DHODHMAPTTP53ALDH1A1 | |
| SCHEMBL8818589 | 0.85 | PARP1 (0.55) | PARP1DHODHMAPTTP53GAA | |
| SCHEMBL8814842 | 0.85 | PARP1 (0.55) | PARP1DHODHMAPTTP53ALDH1A1 | |
| SCHEMBL8892242 | 0.85 | PARP1 (0.55) | PARP1DHODHMAPTTP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997033873-A1 | METHODS OF TREATING OR PREVENTING INTERSTITIAL CYSTITIS | ELI LILLY AND COMPANY (US) | 1997-09-18 | — | — | WO | disclosed |
| WO-1997031635-A1 | METHODS OF TREATING OR PREVENTING SLEEP APNEA | ELI LILLY AND COMPANY (US) | 1997-09-04 | — | — | WO | disclosed |