Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | DAO | P14920 | 2/20 | 0.51 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.51 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.51 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.51 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.51 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.51 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.51 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.51 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.50 |
| ▸ | FEN1 | P39748 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6579538 | 0.80 | GRIN2D (0.53) | KDM4EALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL27030273 | 0.79 | KDM4E (0.53) | KDM4EALDH1A1DAOFEN1HTT | |
| SCHEMBL29830210 | 0.79 | KDM4E (0.53) | KDM4EALDH1A1DAOFEN1HTT | |
| SCHEMBL17504437 | 0.78 | ERCC5 (0.46) | KDM4EALDH1A1DAOGRIN2DGRIN3B | |
| SCHEMBL9393158 | 0.76 | DAO (0.66) | DAOGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL13730103 | 0.75 | ABCG2 (0.53) | KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL2741026 | 0.74 | PDPK1 (0.44) | KDM4EALDH1A1DAOGRIN2DGRIN3B | |
| SCHEMBL31619545 | 0.73 | ERCC5 (0.53) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL6009055 | 0.73 | ERCC5 (0.53) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL12668292 | 0.73 | ERN1 (0.57) | KDM4EALDH1A1DAOERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805809-A2 | AZA AND AZA (N-OXY) ANALOGS OF GLYCINE/NMDA RECEPTOR ANTAGONISTS | State of Oregon through Oregon State Board of Higher Education for and on behalf of Oregon Health Sc. Univ. & Univ. of Oregon (US) | 1997-11-12 | — | — | EP | disclosed |