Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 9/20 | 0.46 |
| ▸ | AKT1 | P31749 | 3/20 | 0.37 |
| ▸ | FEN1 | P39748 | 3/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10156461 | 0.80 | ALOX5AP (0.47) | ALOX5APAKT1 | |
| SCHEMBL872730 | 0.79 | ALOX5AP (0.45) | ALOX5APFEN1PIK3CDPIK3R1SLC6A2 | |
| SCHEMBL10156248 | 0.77 | ALOX5AP (0.51) | ALOX5AP | |
| SCHEMBL881810 | 0.77 | AKT1 (0.38) | ALOX5APAKT1 | |
| SCHEMBL881649 | 0.76 | ALOX5AP (0.41) | ALOX5APFEN1PIK3CDPIK3R1SLC6A2 | |
| SCHEMBL873672 | 0.75 | ALOX5AP (0.42) | ALOX5APFEN1PIK3CDPIK3R1SLC6A2 | |
| SCHEMBL881650 | 0.70 | AKT1 (0.40) | ALOX5APAKT1PIK3CD | |
| SCHEMBL10155961 | 0.70 | ALOX5AP (0.43) | ALOX5AP | |
| SCHEMBL3567997 | 0.67 | AKT1 (0.38) | AKT1 | |
| SCHEMBL882102 | 0.66 | FEN1 (0.46) | ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012040139-A1 | OXADIAZOLE INHIBITORS OF LEUKOTRIENE PRODUCTION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-03-29 | — | — | WO | disclosed |