Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 2/20 | 0.46 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.46 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.46 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.46 |
| ▸ | SRC | P12931 | 11/20 | 0.43 |
| ▸ | ABL1 | P00519 | 3/20 | 0.43 |
| ▸ | EGFR | P00533 | 3/20 | 0.43 |
| ▸ | ABL2 | P42684 | 3/20 | 0.43 |
| ▸ | KDR | P35968 | 2/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8819719 | 0.89 | PI4KA (0.48) | PI4KAPI4K2BPI4K2API4KBSRC | |
| SCHEMBL8819948 | 0.87 | PI4KA (0.36) | PI4KAPI4K2BPI4K2API4KBSRC | |
| SCHEMBL8819681 | 0.85 | EGFR (0.42) | PI4KAPI4K2BPI4K2API4KBSRC | |
| SCHEMBL8819907 | 0.78 | SRC (0.61) | PI4KAPI4K2BPI4K2API4KBSRC | |
| SCHEMBL8819507 | 0.77 | PI4KA (0.47) | PI4KAPI4K2BPI4K2API4KBSRC | |
| SCHEMBL8819471 | 0.74 | PI4KA (0.46) | PI4KAPI4K2BPI4K2API4KBSRC | |
| SCHEMBL8820539 | 0.74 | SRC (0.50) | PI4KAPI4K2BPI4K2API4KBSRC | |
| SCHEMBL8819623 | 0.68 | SRC (0.61) | PI4KAPI4K2BPI4K2API4KBSRC | |
| SCHEMBL18292152 | 0.66 | PI4KA (0.62) | PI4KAPI4K2BPI4K2API4KBSRC | |
| SCHEMBL8820549 | 0.65 | SRC (0.53) | PI4KAPI4K2BPI4K2API4KBSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997049706-A1 | SUBSTITUTED 7-AMINO-PYRROLO[3,2-d]PYRIMIDINES AND THE USE THEREOF | NOVARTIS AG (CH) | 1997-12-31 | — | — | WO | disclosed |