Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 11/20 | 0.55 |
| ▸ | AVPR1A | P37288 | 9/20 | 0.55 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | GLP1R | P43220 | 1/20 | 0.49 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.49 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.49 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8819397 | 0.93 | AVPR2 (0.56) | AVPR2AVPR1A | |
| SCHEMBL8820807 | 0.92 | AVPR2 (0.62) | AVPR2AVPR1AAVPR1B | |
| SCHEMBL8820810 | 0.85 | AVPR2 (0.62) | AVPR2AVPR1A | |
| SCHEMBL8820744 | 0.85 | AVPR2 (0.59) | AVPR2AVPR1A | |
| SCHEMBL8820801 | 0.84 | AVPR2 (0.50) | AVPR2AVPR1AAVPR1B | |
| SCHEMBL8819468 | 0.83 | AVPR2 (0.69) | AVPR2AVPR1A | |
| SCHEMBL8820746 | 0.83 | AVPR2 (0.56) | AVPR2AVPR1A | |
| SCHEMBL8819621 | 0.81 | AVPR2 (0.61) | AVPR2AVPR1A | |
| SCHEMBL8820799 | 0.81 | AVPR2 (0.60) | AVPR2AVPR1A | |
| SCHEMBL8820794 | 0.78 | AVPR2 (0.57) | AVPR2AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997047625-A1 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | AMERICAN CYANAMID COMPANY (US) | 1997-12-18 | — | — | WO | disclosed |