Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 3/20 | 0.55 |
| ▸ | TBXAS1 | P24557 | 10/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8820842 | 0.90 | SRC (0.55) | SRCTBXAS1MAPK1KDM4EALDH1A1 | |
| SCHEMBL8820762 | 0.89 | SRC (0.55) | SRCTBXAS1MAPK1KDM4EALDH1A1 | |
| SCHEMBL8820776 | 0.85 | SRC (0.48) | SRC | |
| SCHEMBL7846964 | 0.79 | SRC (0.70) | SRCTBXAS1 | |
| SCHEMBL7842432 | 0.79 | SRC (0.73) | SRC | |
| SCHEMBL7841904 | 0.79 | SRC (0.81) | SRC | |
| SCHEMBL8819665 | 0.77 | SRC (0.53) | SRC | |
| SCHEMBL7845446 | 0.76 | SRC (0.80) | SRC | |
| SCHEMBL8820549 | 0.76 | SRC (0.53) | SRC | |
| SCHEMBL7834761 | 0.76 | SRC (0.73) | SRCTBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997049706-A1 | SUBSTITUTED 7-AMINO-PYRROLO[3,2-d]PYRIMIDINES AND THE USE THEREOF | NOVARTIS AG (CH) | 1997-12-31 | — | — | WO | claimed |