Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 1/20 | 0.47 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.47 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.47 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 13/20 | 0.44 |
| ▸ | ABL1 | P00519 | 6/20 | 0.44 |
| ▸ | EGFR | P00533 | 6/20 | 0.44 |
| ▸ | ABL2 | P42684 | 6/20 | 0.44 |
| ▸ | CDK1 | P06493 | 2/20 | 0.44 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8820875 | 0.86 | PI4KA (0.46) | PI4KAPI4K2BPI4K2API4KBSRC | |
| SCHEMBL8819667 | 0.86 | SRC (0.35) | PI4KAPI4K2BPI4K2API4KBSRC | |
| SCHEMBL8819716 | 0.84 | PI4KA (0.48) | PI4KAPI4K2BPI4K2API4KBSRC | |
| SCHEMBL8819676 | 0.83 | PI4KA (0.47) | PI4KAPI4K2BPI4K2API4KBSRC | |
| SCHEMBL8819623 | 0.79 | SRC (0.61) | PI4KAPI4K2BPI4K2API4KBSRC | |
| SCHEMBL8819719 | 0.76 | PI4KA (0.48) | PI4KAPI4K2BPI4K2API4KBSRC | |
| SCHEMBL8819980 | 0.74 | PI4KA (0.51) | PI4KAPI4K2BPI4K2API4KBSRC | |
| SCHEMBL8820549 | 0.74 | SRC (0.53) | PI4KAPI4K2BPI4K2API4KBSRC | |
| SCHEMBL8820717 | 0.73 | PI4KB (0.55) | PI4KAPI4K2BPI4K2API4KBSRC | |
| SCHEMBL8820820 | 0.73 | SRC (0.48) | PI4KAPI4K2BPI4K2API4KBSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997049706-A1 | SUBSTITUTED 7-AMINO-PYRROLO[3,2-d]PYRIMIDINES AND THE USE THEREOF | NOVARTIS AG (CH) | 1997-12-31 | — | — | WO | claimed |