Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 4/20 | 0.50 |
| ▸ | AVPR1A | P37288 | 4/20 | 0.50 |
| ▸ | OXTR | P30559 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557173 | 0.88 | AVPR2 (0.55) | AVPR2AVPR1AOXTR | |
| SCHEMBL8820812 | 0.82 | AVPR2 (0.52) | AVPR2AVPR1ATP53 | |
| SCHEMBL8559251 | 0.78 | AVPR2 (0.68) | AVPR2AVPR1AOXTR | |
| SCHEMBL7342405 | 0.78 | AVPR1A (0.48) | AVPR2AVPR1AOXTR | |
| SCHEMBL8559586 | 0.78 | AVPR2 (0.46) | AVPR2AVPR1AOXTR | |
| SCHEMBL8317700 | 0.77 | AVPR2 (0.52) | AVPR2AVPR1AOXTR | |
| SCHEMBL8820852 | 0.76 | AVPR2 (0.49) | AVPR2AVPR1ATP53 | |
| SCHEMBL8317838 | 0.76 | AVPR2 (0.51) | AVPR2AVPR1AOXTR | |
| SCHEMBL8556386 | 0.75 | BCHE (0.52) | AVPR2AVPR1AOXTR | |
| SCHEMBL8563255 | 0.74 | AVPR2 (0.59) | AVPR2AVPR1AOXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997047625-A1 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | AMERICAN CYANAMID COMPANY (US) | 1997-12-18 | — | — | WO | disclosed |