Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 15/20 | 0.50 |
| ▸ | EGFR | P00533 | 8/20 | 0.50 |
| ▸ | ABL1 | P00519 | 6/20 | 0.50 |
| ▸ | ABL2 | P42684 | 6/20 | 0.50 |
| ▸ | KDR | P35968 | 5/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | CDK1 | P06493 | 5/20 | 0.46 |
| ▸ | LCK | P06239 | 2/20 | 0.43 |
| ▸ | TEK | Q02763 | 1/20 | 0.43 |
| ▸ | MPO | P05164 | 1/20 | 0.42 |
| ▸ | TPO | P07202 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | CSK | P41240 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8820771 | 0.92 | SRC (0.49) | SRCEGFRABL1ABL2KDR | |
| SCHEMBL8820841 | 0.91 | SRC (0.61) | SRCEGFRABL1ABL2KDR | |
| SCHEMBL8820549 | 0.87 | SRC (0.53) | SRCEGFRABL1ABL2KDR | |
| SCHEMBL8819645 | 0.87 | SRC (0.47) | SRCEGFRABL1ABL2KDR | |
| SCHEMBL8820762 | 0.84 | SRC (0.55) | SRCMEN1KMT2AALDH1A1 | |
| SCHEMBL8820827 | 0.83 | SRC (0.55) | SRCEGFRABL1ABL2KDR | |
| SCHEMBL8820776 | 0.82 | SRC (0.48) | SRCEGFRABL1ABL2KDR | |
| SCHEMBL8819907 | 0.81 | SRC (0.61) | SRCEGFRABL1ABL2KDR | |
| SCHEMBL8820539 | 0.81 | SRC (0.50) | SRCEGFRABL1ABL2KDR | |
| SCHEMBL8820820 | 0.80 | SRC (0.48) | SRCEGFRABL1ABL2KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997049706-A1 | SUBSTITUTED 7-AMINO-PYRROLO[3,2-d]PYRIMIDINES AND THE USE THEREOF | NOVARTIS AG (CH) | 1997-12-31 | — | — | WO | claimed |