Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 18/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8342324 | 0.86 | GSK3B (0.54) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL13712750 | 0.84 | GSK3B (0.51) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL87861 | 0.80 | GSK3B (0.51) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL88129 | 0.79 | GSK3B (0.55) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL87939 | 0.79 | GSK3B (0.72) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL8232950 | 0.78 | GSK3B (0.57) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL87775 | 0.78 | GSK3B (0.60) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL88128 | 0.77 | GSK3B (0.61) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL8268075 | 0.77 | GSK3B (0.63) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL87922 | 0.77 | GSK3B (0.56) | GSK3BCYP2D6CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129377-B2 | 6-(pyridinyl)-4-pyrimidone derivates as tau protein kinase 1 inhibitors | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2012-03-06 | — | — | US | disclosed |
| US-8129377-B2 | 6-(pyridinyl)-4-pyrimidone derivates as tau protein kinase 1 inhibitors | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2012-03-06 | — | — | US | disclosed |
| WO-2006036015-A2 | 6- (PYRIDINYL) -4-PYRIMIDONE DERIVATES AS TAU PROTEIN KINASE 1 INHIBITORS | MITSUBISHI PHARMA CORPORATION (JP) | 2006-04-06 | — | — | WO | disclosed |