Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 15/20 | 0.72 |
| ▸ | AVPR1A | P37288 | 11/20 | 0.59 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.54 |
| ▸ | OXTR | P30559 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8820810 | 0.92 | AVPR2 (0.62) | AVPR2AVPR1AOXTR | |
| SCHEMBL8819852 | 0.89 | AVPR2 (0.58) | AVPR2AVPR1AAVPR1BOXTR | |
| SCHEMBL8819707 | 0.89 | AVPR2 (0.58) | AVPR2AVPR1AAVPR1B | |
| SCHEMBL8819468 | 0.89 | AVPR2 (0.69) | AVPR2AVPR1AOXTR | |
| SCHEMBL8819981 | 0.87 | AVPR2 (0.61) | AVPR2AVPR1AAVPR1BOXTR | |
| SCHEMBL8819380 | 0.85 | AVPR2 (0.58) | AVPR2AVPR1AAVPR1BOXTR | |
| SCHEMBL8819397 | 0.85 | AVPR2 (0.56) | AVPR2AVPR1AOXTR | |
| SCHEMBL5235081 | 0.84 | AVPR2 (0.74) | AVPR2AVPR1AAVPR1B | |
| SCHEMBL6989178 | 0.84 | AVPR2 (0.69) | AVPR2AVPR1AAVPR1BOXTR | |
| SCHEMBL5235980 | 0.84 | AVPR2 (1.00) | AVPR2AVPR1AAVPR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997047625-A1 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | AMERICAN CYANAMID COMPANY (US) | 1997-12-18 | — | — | WO | disclosed |