SCHEMBL8821

SCHEMBL8821

c1ncc2[nH]ncc2n1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29506231 1.00
Iodide SCHEMBL1296857 0.98 DYRK1A (0.45)
Bromide SCHEMBL26621962 0.98 DYRK1A (0.45)
Hydrochloric Acid SCHEMBL18284548 0.98 DYRK1A (0.45)
Ammonia Solution, Strong SCHEMBL28492555 0.98 DYRK1A (0.45)
SCHEMBL4222803 0.98 DYRK1A (0.45)
Phosphine SCHEMBL27502321 0.98 DYRK1A (0.45)
Cyanide SCHEMBL27725574 0.96 DYRK1A (0.44)
Hydrazine SCHEMBL28204704 0.96 DYRK1A (0.44)
SCHEMBL26621980 0.92 DYRK1A (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 20508 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12590094-B2 Compounds for the treatment of neurodegenerative and metabolic disorders UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2026-03-31 US claimed
EP-3597184-B1 INDANONE DERIVATIVES, PHARMACEUTICALLY ACCEPTABLE SALTS OR OPTICAL ISOMERS THEREOF, PREPARATION METHOD FOR SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING VIRAL DISEASES KOREA RES INST CHEMICAL TECH (KR) 2026-03-04 EP claimed
US-20260055112-A1 CRYSTALLINE FORM OF PYRAZOLOPYRIMIDINE ESTER COMPOUND AND METHODS OF PREPARING THE SAME SHANGHAI MAIUS PHARMACEUTICAL CO. LTD. (CN) 2026-02-26 US claimed
EP-4396191-B1 COMPOUNDS USEFUL IN MODULATION OF AHR SIGNALLING JAGUAHR THERAPEUTICS PTE LTD (SG) 2026-02-18 EP claimed
US-20260042780-A1 CERTAIN CHEMICAL ENTITIES, COMPOSITIONS AND METHODS INTELLIKINE LLC (US) 2026-02-12 US claimed
US-20260027096-A1 PHD INHIBITORS UNIV OXFORD INNOVATION LTD (GB) 2026-01-29 US claimed
EP-4219501-B1 COMPOUND CONTAINING 2,4-THIAZOLE RING, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF UNIV SHANDONG (CN) 2026-01-28 EP claimed
US-20250388599-A1 TRICYCLIC PI3K INHIBITOR COMPOUNDS AND METHODS OF USE GENENTECH INC (US) 2025-12-25 US claimed
EP-4655288-A1 PHD INHIBITORS Oxford University Innovation Limited (GB) 2025-12-03 EP claimed
US-12441731-B2 Pyrazolopyrimidine compounds and uses thereof INCYTE CORPORATION (US) 2025-10-14 US claimed
CN-87103904-A Weedicide 1988-02-10 CN claimed
EP-0244097-A2 Pyrazolopyrimidine herbicides SCHERING AGROCHEMICALS LIMITED (GB) 1987-11-04 EP claimed
EP-0244170-A2 Silver halide photographic light-sensitive material and method of processing thereof KONICA CORPORATION (JP) 1987-11-04 EP claimed
WO-1987004321-A2 USE OF HETEROCYCLIC NITROGEN-CONTAINING COMPOUNDS FOR REDUCING MOISTURE LOSS FROM PLANTS AND INCREASING CROP YIELD RHONE-POULENC NEDERLANDS B.V. (NL) 1987-07-30 WO claimed
US-4654348-A Pyrazolo[4,3-d]pyrimidine derivative, process for its production, antihyperlipidemic agent containing it, its intermediate, and process for the production of the intermediate NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1987-03-31 US claimed
EP-0210653-A2 Pyrazolo [4,3-d] pyrimidine derivative, process for its production, and antihyperlipidemic or antiatheroschlerotic agent containing it NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1987-02-04 EP claimed
EP-0157415-A2 Pyrazolo[4,3-d] pyrimidine derivative process for its production antihyperlipidemic agent containing it, its intermediate, and process for the production of the intermediate NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1985-10-09 EP claimed
EP-0034038-B1 USE OF SILVER HALIDE DEVELOPMENT ACCELERATORS, PHOTOGRAPHIC FILMS AND PROCESSES FOR DEVELOPING LITHOGRAFIC FILM E.I. DU PONT DE NEMOURS AND COMPANY (US) 1984-05-30 EP claimed
EP-0095289-A2 Imidazo(1,2-c)pyrazolo(3,4-e)pyrimidines and their production WARNER-LAMBERT COMPANY (US) 1983-11-30 EP claimed
US-4163846-A HERBICIDES FISONS LIMITED (GB) 1979-08-07 US claimed