⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2241562 | 1.00 | — | — | |
| SCHEMBL2241560 | 1.00 | — | — | |
| SCHEMBL10066350 | 0.74 | — | — | |
| SCHEMBL7992428 | 0.74 | — | — | |
| SCHEMBL8077995 | 0.72 | — | — | |
| SCHEMBL21191554 | 0.72 | — | — | |
| SCHEMBL17540027 | 0.72 | — | — | |
| SCHEMBL8280822 | 0.71 | — | — | |
| SCHEMBL242680 | 0.71 | — | — | |
| SCHEMBL14639585 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3383860-B1 | APELIN RECEPTOR AGONISTS AND METHODS OF USE | BRISTOL MYERS SQUIBB CO (US) | 2021-01-20 | — | — | EP | disclosed |
| WO-2020146532-A1 | METALLOENZYME INHIBITOR COMPOUNDS | SPARKS STEVEN (US) | 2020-07-16 | — | — | WO | disclosed |
| US-10656522-B2 | Composition for forming fine resist pattern and pattern forming method using same | AZ ELECTRONIC MATERIALS (LUXEMBOURG) S.A.R.L. (LU) | 2020-05-19 | — | — | US | disclosed |
| US-9889136-B2 | Tetrahydropyridopyrimidine compound or salt thereof | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2018-02-13 | — | — | US | disclosed |
| US-20170305859-A1 | An Anticonvulsant Compound | ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE (GB) | 2017-10-26 | — | — | US | disclosed |
| WO-2017165640-A1 | 6-HYDROXY-4-OXO-1,4-DIHYDROPYRIMIDINE-5-CARBOXAMIDES AS APJ AGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-09-28 | — | — | WO | disclosed |
| US-20170267695-A1 | ERK INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2017-09-21 | — | — | US | disclosed |
| WO-2017106396-A1 | HETEROARYLHYDROXYPYRIMIDINONES AS AGONISTS OF THE APJ RECEPTOR | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-06-22 | — | — | WO | disclosed |
| WO-2017096130-A1 | APELIN RECEPTOR AGONISTS AND METHODS OF USE | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-06-08 | — | — | WO | disclosed |
| US-9624194-B2 | Heteroaryl compounds as sodium channel blockers | PURDUE PHARMA L.P. (US) | 2017-04-18 | — | — | US | disclosed |
| WO-2013102431-A1 | THERAPEUTICALLY ACTIVE COMPOUNDS AND THEIR METHODS OF USE | AGIOS PHARMACEUTICALS, INC. (US) | 2013-07-11 | — | — | WO | disclosed |
| WO-2013023000-A2 | SMALL MOLECULE COMPOUNDS THAT CONTROL MAMMAL-PATHOGENIC NEMATODES | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2013-02-14 | — | — | WO | disclosed |
| WO-2013022985-A2 | SMALL MOLECULE COMPOUNDS FOR THE CONTROL OF NEMATODES | BOYCE THOMPSON INSTITUTE FOR PLANT RESEARCH (US) | 2013-02-14 | — | — | WO | disclosed |
| WO-2013022996-A2 | THE UTILITY OF NEMATODE SMALL MOLECULES | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2013-02-14 | — | — | WO | disclosed |
| WO-2012040040-A1 | HCV NS3 PROTEASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2012-03-29 | — | — | WO | disclosed |
| US-7772431-B1 | Performance of energy storage devices: potential areas for dendritic chemistry involvement | NEWKOME GEORGE R | 2010-08-10 | — | — | US | disclosed |
| EP-2013202-B1 | SUBSTITUTED PYRAZINONE DERIVATIVES FOR USE AS A MEDICINE | JANSSEN PHARMACEUTICA NV (BE) | 2010-06-16 | — | — | EP | disclosed |
| WO-2008001070-A1 | PYRIMIDINE DERIVATIVES USEFUL IN THE TREATMENT OF CANCER | ASTRAZENECA AB (SE) | 2008-01-03 | — | — | WO | disclosed |
| US-20070054903-A1 | Bis-aryl kinase inhibitors and method | AMGEN INC. (US) | 2007-03-08 | — | — | US | disclosed |
| US-20070027156-A1 | Crf antagonists and heterobicyclic compounds | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-02-01 | — | — | US | disclosed |