⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18629124 | 0.80 | — | — | |
| SCHEMBL18863926 | 0.76 | — | — | |
| SCHEMBL78483 | 0.74 | — | — | |
| SCHEMBL18373286 | 0.73 | — | — | |
| SCHEMBL16374077 | 0.73 | — | — | |
| SCHEMBL16374083 | 0.73 | — | — | |
| SCHEMBL10042025 | 0.73 | — | — | |
| SCHEMBL11300053 | 0.73 | — | — | |
| SCHEMBL13190649 | 0.73 | — | — | |
| SCHEMBL22745225 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239828-A1 | MANNOSE 6-PHOSPHATE OR ASGPR RECEPTOR BINDING COMPOUNDS FOR THE DEGRADATION OF EXTRACELLULAR PROTEINS | AVILAR THERAPEUTICS, INC. (US) | 2024-07-18 | — | — | US | disclosed |
| US-20240072809-A1 | ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF EXTRACELLULAR PROTEINS | AVILAR THERAPEUTICS, INC. (US) | 2024-02-29 | — | — | US | disclosed |
| US-11819551-B2 | ASGPR-binding compounds for the degradation of extracellular proteins | AVILAR THERAPEUTICS, INC. (US) | 2023-11-21 | — | — | US | disclosed |
| US-20230322996-A1 | POLYMER-INTERACTION MOLECULE CONJUGATES AND METHODS OF USE | LIFE TECHNOLOGIES AS (NO) | 2023-10-12 | — | — | US | disclosed |
| US-20230233689-A1 | Bifunctional Small Molecules to Target the Selective Degradation of Circulating Proteins | UNIV YALE (US) | 2023-07-27 | — | — | US | disclosed |
| US-20180133137-A1 | PROCESS FOR TREATING KERATIN MATERIALS USING AMIDE, ACID OR ESTER C-GLYCOSIDE DERIVATIVES, AND COSMETIC COMPOSITION CONTAINING SAME | L'OREAL (FR) | 2018-05-17 | — | — | US | disclosed |
| US-20180065960-A1 | QUINOLONE DERIVATIVES AS FIBROBLAST GROWTH FACTOR RECEPTOR INHIBITORS | PRINCIPIA BIOPHARMA INC. | 2018-03-08 | — | — | US | disclosed |
| US-9815834-B2 | Quinolone derivatives as fibroblast growth factor receptor inhibitors | PRINCIPIA BIOPHARMA, INC. (US) | 2017-11-14 | — | — | US | disclosed |
| US-9567334-B2 | Quinolone derivatives as fibroblast growth factor receptor inhibitors | PRINCIPIA BIOPHARMA, INC. (US) | 2017-02-14 | — | — | US | disclosed |
| WO-2016172631-A2 | SUBSTRATE SELECTIVE INHIBITORS OF INSULIN-DEGRADING ENZYME (IDE) AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-10-27 | — | — | WO | disclosed |
| EP-0494906-A1 | METHOD FOR CONTINUOUS PRODUCTION OF $g(D)1-ENOL ETHERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-07-22 | — | — | EP | disclosed |
| US-5103017-A | PYRAZOLINES AND THEIR USE AS SAFENERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-04-07 | — | — | US | disclosed |
| EP-0439835-A2 | Process for the preparation of pyrazolecarboxylic acid derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-08-07 | — | — | EP | disclosed |
| US-5037468-A | Prevent phytotoxic damage by herbicides | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-08-06 | — | — | US | disclosed |
| US-5013444-A | Process for separating off enol ethers from reaction mixtures containing alcohols | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-05-07 | — | — | US | disclosed |
| WO-1991004956-A1 | METHOD FOR CONTINUOUS PRODUCTION OF Δ1-ENOL ETHERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-04-18 | — | — | WO | disclosed |
| EP-0415334-A1 | Process for separation of enol ethers from mixtures thereof with alcohols | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-03-06 | — | — | EP | disclosed |
| US-4990602-A | Bactericides | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1991-02-05 | — | — | US | disclosed |
| EP-0409118-A1 | Pyrazolines and their use as antidotes | Hoechst Schering AgrEvo GmbH (DE) | 1991-01-23 | — | — | EP | disclosed |
| EP-0272110-A2 | Erythromycin a derivatives and method for the preparation of the same | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1988-06-22 | — | — | EP | disclosed |