Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.53 |
| ▸ | PDE4A | P27815 | 1/20 | 0.53 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.53 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.53 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.49 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7345049 | 0.85 | TSHR (0.76) | TSHRALDH1A1PDE4APDE4BPDE4C | |
| SCHEMBL30592391 | 0.83 | SMN1; SMN2 (0.74) | TSHRALDH1A1NOTUMSMN1; SMN2MAPT | |
| SCHEMBL330273 | 0.83 | SMN1; SMN2 (0.74) | TSHRALDH1A1NOTUMSMN1; SMN2MAPT | |
| SCHEMBL7349843 | 0.80 | AVPR2 (0.72) | TSHRALDH1A1LMNAHPGDKMT2A | |
| SCHEMBL4863174 | 0.78 | SMN1; SMN2 (0.67) | TSHRALDH1A1NOTUMSMN1; SMN2MAPT | |
| SCHEMBL4861742 | 0.77 | MAPT (0.72) | ALDH1A1SMN1; SMN2MAPTLMNAPKM | |
| SCHEMBL23632960 | 0.77 | MEN1 (0.53) | TSHRALDH1A1NOTUMPDE4APDE4B | |
| SCHEMBL30898774 | 0.77 | MEN1 (0.53) | TSHRALDH1A1NOTUMPDE4APDE4B | |
| SCHEMBL7359695 | 0.77 | AVPR1A (0.67) | AVPR1A | |
| SCHEMBL19260249 | 0.77 | HDAC1 (0.72) | ALDH1A1MAPTKDM4EGAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997049668-A1 | INHIBITIORS OF CYSTEINE PROTEASE | SMITHKLINE BEECHAM CORPORATION (US) | 1997-12-31 | — | — | WO | disclosed |