Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | SIRT2 | Q8IXJ6 | 8/20 | 0.49 |
| ▸ | SIRT1 | Q96EB6 | 7/20 | 0.49 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.48 |
| ▸ | TLR2 | O60603 | 2/20 | 0.48 |
| ▸ | SIRT3 | Q9NTG7 | 4/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8823937 | 0.93 | PTPN1 (0.51) | KMT2A | |
| SCHEMBL29370715 | 0.88 | FOLH1 (0.62) | KMT2AHDAC1HDAC2SIRT2SIRT1 | |
| SCHEMBL8823890 | 0.88 | FOLH1 (0.62) | KMT2AHDAC1HDAC2SIRT2SIRT1 | |
| SCHEMBL29401850 | 0.88 | FOLH1 (0.62) | KMT2AHDAC1HDAC2SIRT2SIRT1 | |
| SCHEMBL31624479 | 0.88 | FOLH1 (0.62) | KMT2AHDAC1HDAC2SIRT2SIRT1 | |
| SCHEMBL178700 | 0.88 | FOLH1 (0.62) | KMT2AHDAC1HDAC2SIRT2SIRT1 | |
| SCHEMBL178815 | 0.88 | FOLH1 (0.62) | KMT2AHDAC1HDAC2SIRT2SIRT1 | |
| SCHEMBL29401164 | 0.88 | FOLH1 (0.62) | KMT2AHDAC1HDAC2SIRT2SIRT1 | |
| SCHEMBL22804067 | 0.88 | FOLH1 (0.62) | KMT2AHDAC1HDAC2SIRT2SIRT1 | |
| SCHEMBL27142958 | 0.88 | FOLH1 (0.62) | KMT2AHDAC1HDAC2SIRT2SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997049668-A1 | INHIBITIORS OF CYSTEINE PROTEASE | SMITHKLINE BEECHAM CORPORATION (US) | 1997-12-31 | — | — | WO | disclosed |