Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL882410 | 0.79 | ALOX5AP (0.44) | CYP11B1CYP11B2ALOX5APFEN1 | |
| SCHEMBL882408 | 0.74 | CCR1 (0.52) | KDM4E | |
| SCHEMBL882393 | 0.72 | KDM4E (0.50) | KDM4ECYP11B1CYP11B2 | |
| SCHEMBL22736534 | 0.69 | SLC6A2 (0.36) | — | |
| SCHEMBL10149770 | 0.66 | ALOX5AP (0.37) | KDM4EALOX5AP | |
| SCHEMBL12891847 | 0.66 | SLC6A2 (0.36) | — | |
| SCHEMBL12891848 | 0.66 | SLC6A2 (0.36) | — | |
| SCHEMBL12891658 | 0.66 | SLC6A2 (0.42) | — | |
| SCHEMBL10161845 | 0.63 | PIK3CG (0.42) | KDM4EALOX5APFEN1 | |
| SCHEMBL15871270 | 0.60 | CYP11B1 (0.41) | CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012040137-A1 | OXADIAZOLE INHIBITORS OF LEUKOTRIENE PRODUCTION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-03-29 | — | — | WO | disclosed |