Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | PGD | P52209 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | GALR3 | O60755 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1581133 | 1.00 | TDP1 (0.53) | TDP1TSHRTRPV1PGDCHRM2 | |
| SCHEMBL7792932 | 0.92 | TDP1 (0.67) | TDP1TSHRTRPV1PGDCHRM2 | |
| SCHEMBL6817132 | 0.92 | TDP1 (0.67) | TDP1TSHRTRPV1PGDCHRM2 | |
| SCHEMBL2100980 | 0.92 | TDP1 (0.67) | TDP1TSHRTRPV1PGDCHRM2 | |
| SCHEMBL4799141 | 0.92 | TDP1 (0.50) | TDP1TSHRTRPV1PGDCHRM2 | |
| SCHEMBL1581172 | 0.89 | TDP1 (0.62) | TDP1TSHRTRPV1ABCB1ALDH1A1 | |
| SCHEMBL17239658 | 0.89 | TDP1 (0.73) | TDP1TSHRTRPV1ABCB1ALDH1A1 | |
| SCHEMBL20607560 | 0.89 | TDP1 (0.73) | TDP1TSHRTRPV1ABCB1ALDH1A1 | |
| SCHEMBL2377272 | 0.89 | TDP1 (0.62) | TDP1TSHRTRPV1ABCB1ALDH1A1 | |
| SCHEMBL9577881 | 0.89 | TDP1 (0.62) | TDP1TSHRTRPV1ABCB1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5696245-A | HEATING A MIXTURE OF SUCROSE, AN ACID CATALYST SUCH AS CITRIC ACID AND A NATURAL OR SYNTHETIC POLYMER; FRUCTOSE OXOCARBONIUM ION INTERMEDIATE | THE UNIVERSITY OF MONTANA (US) | 1997-12-09 | — | — | US | disclosed |