Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | CES2 | O00748 | 2/20 | 0.35 |
| ▸ | CES1 | P23141 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL72683 | 1.00 | TDP1 (0.42) | TDP1ALDH1A1LMNASRD5A2CA2 | |
| SCHEMBL27955132 | 1.00 | TDP1 (0.42) | TDP1ALDH1A1LMNASRD5A2CA2 | |
| SCHEMBL72172 | 1.00 | TDP1 (0.42) | TDP1ALDH1A1LMNASRD5A2CA2 | |
| SCHEMBL5461407 | 1.00 | TDP1 (0.42) | TDP1ALDH1A1LMNASRD5A2CA2 | |
| SCHEMBL6532888 | 1.00 | TDP1 (0.42) | TDP1ALDH1A1LMNASRD5A2CA2 | |
| SCHEMBL2986285 | 1.00 | TDP1 (0.42) | TDP1ALDH1A1LMNASRD5A2CA2 | |
| SCHEMBL7348978 | 0.99 | TDP1 (0.41) | TDP1ALDH1A1LMNASRD5A2CA2 | |
| SCHEMBL7355024 | 0.99 | TDP1 (0.41) | TDP1ALDH1A1LMNASRD5A2CA2 | |
| Water SCHEMBL3859938 | 0.99 | TDP1 (0.41) | TDP1ALDH1A1LMNASRD5A2CA2 | |
| Water SCHEMBL1322825 | 0.99 | TDP1 (0.41) | TDP1ALDH1A1LMNASRD5A2CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3826 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12441745-B2 | Processes and compounds | RADIUS PHARMACEUTICALS, INC. (US) | 2025-10-14 | — | — | US | claimed |
| CN-119954778-A | Synthesis method of lenacipam sodium and series of intermediate compounds thereof | 杭州科巢生物科技有限公司 | 2025-05-09 | — | — | CN | claimed |
| CN-119569588-A | Preparation method and intermediate of ilast hydrochloride | 杭州诺澳生物医药科技有限公司 | 2025-03-07 | — | — | CN | claimed |
| CN-119409612-A | Resolution refining method of clemastine fumarate | 南京斯泰尔医药科技有限公司 | 2025-02-11 | — | — | CN | claimed |
| CN-113348163-B | Methods and compounds | 雷迪厄斯制药公司 | 2024-10-08 | — | — | CN | claimed |
| CN-117964625-A | Preparation method of high-optical-purity ponatinib intermediate | 安徽万邦医药科技股份有限公司 | 2024-05-03 | — | — | CN | claimed |
| CN-117843552-A | Resolution method of cis-4-amino-3-methoxypiperidine-1-formate optical isomer | 中国医学科学院药物研究所 | 2024-04-09 | — | — | CN | claimed |
| CN-117843454-A | Menthol slow-release eutectic compound and preparation method and application thereof | 湖北中烟工业有限责任公司 | 2024-04-09 | — | — | CN | claimed |
| US-11905292-B2 | Process and intermediates for preparing a JAK inhibitor | INCYTE CORPORATION (US) | 2024-02-20 | — | — | US | claimed |
| CN-116761792-A | Methods and intermediates for preparing JAK inhibitors | 因赛特公司 | 2023-09-15 | — | — | CN | claimed |
| EP-0539460-B1 | SALTS DERIVED FROM DIALKYLAMINOALKYLSULPHONYL-26 PRISTINAMYCIN II B | RHONE POULENC RORER SA (FR) | 1994-10-05 | — | — | EP | claimed |
| EP-0575482-A1 | ANTIVIRAL ACTIVITY AND RESOLUTION OF 2-HYDROXYMETHYL-5-(5-FLUOROCYTOSIN-1-YL)-1,3-OXATHIOLANE | EMORY UNIVERSITY (US) | 1993-12-29 | — | — | EP | claimed |
| EP-0539460-A1 | SALTS DERIVED FROM DIALKYLAMINOALKYLSULPHONYL-26 PRISTINAMYCIN II B. | RHONE POULENC RORER SA (FR) | 1993-05-05 | — | — | EP | claimed |
| WO-1992014743-A2 | ANTIVIRAL ACTIVITY AND RESOLUTION OF 2-HYDROXYMETHYL-5-(5-FLUOROCYTOSIN-1-YL)-1,3-OXATHIOLANE | EMORY UNIVERSITY (US) | 1992-09-03 | — | — | WO | claimed |
| WO-1992001694-A1 | NEW SALTS DERIVED FROM DIALKYLAMINOALKYLSULPHONYL-26 PRISTINAMYCIN II¿B? | RHONE-POULENC RORER S.A. (FR) | 1992-02-06 | — | — | WO | claimed |
| EP-0365213-A2 | Method of resolving cis 3-amino-4-[2-(2-furyl)vinyl]-1-methoxy-carbonylmethyl-azetidin-2-one and di-p-toluoyl-tartaric acid salts thereof | ELI LILLY AND COMPANY (US) | 1990-04-25 | — | — | EP | claimed |
| EP-0251904-B1 | PROCESS FOR THE PREPARATION OF ACIDIC LEVOMEPROMAZINE MALEATE | RHONE-POULENC SANTE (FR) | 1990-01-10 | — | — | EP | claimed |
| US-4798895-A | Process for preparing levomepromazine hydrogen maleate | RHONE-POULENC SANTE (FR) | 1989-01-17 | — | — | US | claimed |
| US-4471121-A | Method of resolving trans-d alpha-1-n-propyl-6-oxodecahydroquinoline and di-p-toluoyltartaric acid salts thereof | ELI LILLY AND COMPANY (US) | 1984-09-11 | — | — | US | claimed |
| EP-0112604-A1 | Novel resolved keto compounds and process | ELI LILLY AND COMPANY (US) | 1984-07-04 | — | — | EP | claimed |